Prions, urinary gonadotrophins and recombinant gonadotrophins

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Recombinant versus urinary gonadotrophins for triggering ovulation in assisted conception.

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Transgenic animals and gonadotrophins.

A variety of transgenic animal models has been developed to elucidate in vivo the functions of gonadotrophin genes. Some of these have focused on regulatory aspects through expression of gonadotrophin subunit promoter-driven reporter genes. Others have been carried out by overexpression or targeted disruption of specific gonadotrophin subunit genes, or by eliminating pituitary gonadotroph cells...

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Bye-bye urinary gonadotrophins? Recombinant FSH: a real progress in ovulation induction and IVF?

Whether recombinant gonadotrophin products do, indeed, represent progress for routine ovulation induction and IVF cycles, in comparison with urinary products, has remained controversial. Here we review published data with regard to respective risks, outcomes and cost for both medication options. Safety considerations favour recombinant products, while overall outcome and cost considerations fav...

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Meta-analysis of recombinant FSH and urinary-derived gonadotrophins for IVF or ICSI.

Di Simone, N., Ferrazzani, S., Castellani, R., De Carolis, S., Manscuso, S. and Caruso, A. (1997) Heparin and low dose aspirin restore placental human chorionic gonadotrophin secretion abolished by antiphospholipid antibodycontaining sera. Hum. Reprod., 12, 2061±2065. Di Simone, N., Meroni, P.L., del Papa, N., Raschi, E., Caliandro, D., De Carolis, C.S., Khamashta, M.A., Atsumi, T., Hughes, G.R...

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Urinary gonadotrophins but not recombinant gonadotrophins reduce expression of VEGF120 and its receptors flt-1 and flk-1 in the mouse uterus during the peri-implantation period.

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2003

ISSN: 1460-2350

DOI: 10.1093/humrep/deg176